منابع مشابه
The histopathological effects of chronic electrical stimulation of the cat cochlea.
The success of a cochlear implant depends on stimulating an adequate number of viable spiral ganglion cells. The effect of chronic electrical stimulation on ganglion cells is therefore an important consideration when assessing the effectiveness and safety of such a device. The histopathological assessment of chronic unstimulated intracochlear electrodes is now well documented (Simmons, 1967; Cl...
متن کاملEffects of phase duration on detection of electrical stimulation of the human cochlea.
Detection thresholds for biphasic symmetric pulses were measured in fourteen human subjects implanted with the Cochlear Corporation Nucleus 22 Implant. The effects of phase duration on thresholds were studied using single pulses, and 500 ms pulse trains at 100 pps. Psychophysical detection thresholds decreased as a function of phase duration with a change in slope at approximately 0.5 ms/phase....
متن کاملFunctional MRI of auditory cortex activated by multisite electrical stimulation of the cochlea.
Electrical stimulation of the ear of deaf patients via cochlear implants offers a unique occasion to study activity of central auditory pathways with fMRI, without bias due to scanner noise. Such measurements, however, require one to control the possible interference between fMRI acquisition and the implanted electrodes. A series of measurements on a customized phantom designed to characterize ...
متن کاملSpatial distribution of neural activity evoked by electrical stimulation of the cochlea.
Activity in the central auditory system was mapped with 2-deoxyglucose (2-DG) autoradiography, using either pure tones or electrical stimulation of the normal cochlea. Electrical stimulation with both monopolar (distant reference electrode) and bipolar prostheses near threshold increased 2-DG uptake in auditory nuclei in a manner similar to that seen with a pure tone: increased 2-DG uptake was ...
متن کاملElectrical Stimulation of Spiral Ganglion Cells in the Human Cochlea: A 3D Model
Electrical stimulation of auditory nerve fibers by cochlear implant electrodes has been an approved clinical practice to restore the hearing sensation in profoundly deaf people. Profound deafness is largely attributed to the loss of hair cells and subsequent decay of peripheral processes of auditory nerve fibers in the cochlea. In such pathological condition, spiral ganglion cells (SGN) which a...
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ژورنال
عنوان ژورنال: Nature
سال: 1937
ISSN: 0028-0836,1476-4687
DOI: 10.1038/139633b0